SB25-10/11: ASUM Transportation Fee

SB25-10/11: ASUM Transportation Fee. This resolution passed during the March 9, 2011 meeting of the Associated Students of the University of Montana (ASUM)

Springbrook: Challenges in developing a long-term, rainforest wireless sensor network

We describe the design, development and learnings from the first phase of a rainforest ecological sensor network at Springbrook - part of a World Heritage precinct in South East Queensland. This first phase is part of a major initiative to develop the capability to provide reliable, long-term monitoring of rainforest ecosystems. We focus in particular on our analysis around energy and communication challenges which need to be solved to allow for reliable, long-term deployments in these types of environments

Collaboration and Mentorship in the Organization of an American Indian Family Collection: A Case Study in Service Learning at the University of Oklahoma

This case study examines an experiment in archival practice and mentorship undertaken at the University of Oklahoma (OU) during the spring semester of 2019. The project concerned the inventory of an important privately held archive in American Indian history. The case study describes the process and documentation involved in an institution assuming temporary custody of a private collection, including legal and ethical considerations of temporary custody, and explores the mentorship relationship among group of interdisciplinary faculty and students, as well as the products, both archival and non-archival, that resulted form this collaborative effort

Reionization of the Local Group of Galaxies

We present the first detailed structure formation and radiative transfer simulations of the reionization history of our cosmic neighbourhood. To this end, we follow the formation of the Local Group of galaxies and nearby clusters by means of constrained simulations, which use the available observational constraints to construct a representation of those structures which reproduces their actual positions and properties at the present time. We find that the reionization history of the Local Group is strongly dependent on the assumed photon production efficiencies of the ionizing sources, which are still poorly constrained. If sources are relatively efficient, i.e. the process is 'photon-rich', the Local Group is primarily ionized externally by the nearby clusters. Alternatively, if the sources are inefficient, i.e. reionization is 'photon-poor' the Local Group evolves largely isolated and reionizes itself. The mode of reionization, external vs. internal, has important implications for the evolution of our neighbourhood, in terms of e.g. its satellite galaxy populations and primordial stellar populations. This therefore provides an important avenue for understanding the young universe by detailed studies of our nearby structures.Comment: 10 pages, 8 figures (all in colour), submitted to MNRA

RIN4 Interacts with Pseudomonas syringae Type III Effector Molecules and Is Required for RPM1-Mediated Resistance in Arabidopsis

In Arabidopsis, RPM1 confers resistance against Pseudomonas syringae expressing either of two sequence unrelated type III effectors, AvrRpm1 or AvrB. An RPM1-interacting protein (RIN4) coimmunoprecipitates from plant cell extracts with AvrB, AvrRpm1, or RPM1. Reduction of RIN4 protein levels inhibits both the hypersensitive response and the restriction of pathogen growth controlled by RPM1. RIN4 reduction causes diminution of RPM1. RIN4 reduction results in heightened resistance to virulent Peronospora parasitica and P. syringae, and ectopic defense gene expression. Thus, RIN4 positively regulates RPM1-mediated resistance yet is, formally, a negative regulator of basal defense responses. AvrRpm1 and AvrB induce RIN4 phosphorylation. This may enhance RIN4 activity as a negative regulator of plant defense, facilitating pathogen growth. RPM1 may "guard" against pathogens that use AvrRpm1 and AvrB to manipulate RIN4 activity

Does the Fornax dwarf spheroidal have a central cusp or core?

The dark matter dominated Fornax dwarf spheroidal has five globular clusters orbiting at ~1 kpc from its centre. In a cuspy CDM halo the globulars would sink to the centre from their current positions within a few Gyrs, presenting a puzzle as to why they survive undigested at the present epoch. We show that a solution to this timing problem is to adopt a cored dark matter halo. We use numerical simulations and analytic calculations to show that, under these conditions, the sinking time becomes many Hubble times; the globulars effectively stall at the dark matter core radius. We conclude that the Fornax dwarf spheroidal has a shallow inner density profile with a core radius constrained by the observed positions of its globular clusters. If the phase space density of the core is primordial then it implies a warm dark matter particle and gives an upper limit to its mass of ~0.5 keV, consistent with that required to significantly alleviate the substructure problem.Comment: 6 pages, 5 figures, accepted for publication in MNRAS, high resolution simulations include

Collaboration and Mentorship in the Organization of an American Indian Family Collection: A Case Study in Service Learning at the University of Oklahoma

This case study examines an experiment in archival practice and mentorship undertaken at the University of Oklahoma (OU) during the spring semester of 2019. The project concerned the inventory of an important privately held archive in American Indian history. The case study describes the process and documentation involved in an institution assuming temporary custody of a private collection, including legal and ethical considerations of temporary custody, and explores the mentorship relationship among group of interdisciplinary faculty and students, as well as the products, both archival and non-archival, that resulted form this collaborative effort.Ye

Identification of a candidate gene for astigmatism

PURPOSE. Astigmatism is a common refractive error that reduces vision, where the curvature and refractive power of the cornea in one meridian are less than those of the perpendicular axis. It is a complex trait likely to be influenced by both genetic and environmental factors. Twin studies of astigmatism have found approximately 60% of phenotypic variance is explained by genetic factors. This study aimed to identify susceptibility loci for astigmatism

Identification of KIF21A mutations as a rare cause of congenital fibrosis of the extraocular muscles type 3 (CFEOM3).

PURPOSE. Three congenital fibrosis of the extraocular muscles phenotypes (CFEOM1-3) have been identified. Each represents a specific form of paralytic strabismus characterized by congenital restrictive ophthalmoplegia, often with accompanying ptosis. It has been demonstrated that CFEOM1 results from mutations in KIF21A and CFEOM2 from mutations in PHOX2A. This study was conducted to determine the incidence of KIF21A and PHOX2A mutations among individuals with the third CFEOM phenotype, CFEOM3. METHODS. All pedigrees and sporadic individuals with CFEOM3 in the authors' database were identified, whether the pedigrees were linked or consistent with linkage to the FEOM1, FEOM2, and/or FEOM3 loci was determined, and the appropriate pedigrees and the sporadic individuals were screened for mutations in KIF21A and PHOX2A. RESULTS. Twelve CFEOM3 pedigrees and 10 CFEOM3 sporadic individuals were identified in the database. The structures of eight of the pedigrees permitted the generation of meaningful linkage data. KIF21A was screened in 17 probands, and mutations were identified in two CFEOM3 pedigrees. One pedigree harbored a novel mutation (2841G-->A, M947I) and one harbored the most common and recurrent of the CFEOM1 mutations identified previously (2860C-->T, R954W). None of CFEOM3 pedigrees or sporadic individuals harbored mutations in PHOX2A. CONCLUSIONS. The results demonstrate that KIF21A mutations are a rare cause of CFEOM3 and that KIF21A mutations can be nonpenetrant. Although KIF21A is the first gene to be associated with CFEOM3, the results imply that mutations in the unidentified FEOM3 gene are the more common cause of this phenotype

Protein–protein interactions as a proxy to monitor conformational changes and activation states of the tomato resistance protein I-2

Plant resistance proteins (R) are involved in pathogen recognition and subsequent initiation of defence responses. Their activity is regulated by inter- and intramolecular interactions. In a yeast two-hybrid screen two clones (I2I-1 and I2I-2) specifically interacting with I-2, a Fusarium oxysporum f. sp. lycopersici resistance protein of the CC-NB-LRR family, were identified. Sequence analysis revealed that I2I-1 belongs to the Formin gene family (SlFormin) whereas I2I-2 has homology to translin-associated protein X (SlTrax). SlFormin required only the N-terminal CC I-2 domain for binding, whereas SlTrax required both I-2 CC and part of the NB-ARC domain. Tomato plants stably silenced for these interactors were not compromised in I-2-mediated disease resistance. When extended or mutated forms of I-2 were used as baits, distinct and often opposite, interaction patterns with the two interactors were observed. These interaction patterns correlated with the proposed activation state of I-2 implying that active and inactive R proteins adopt distinct conformations. It is concluded that the yeast two hybrid system can be used as a proxy to monitor these different conformational states